Searchable abstracts of presentations at key conferences in endocrinology

ea0081rc3.7 | Rapid Communications 3: Thyroid 1 | ECE2022

Immune-related thyroid dysfunctions during PD-1/PD-L1 inhibitors and their association to the oncological outcome: new evidence

Ferrari Matteo , Anna Nervo Alice , Basile Sara , Migliore Enrica , D'Angelo Valentina , Gruosso Giovanni , Rosso Daniela , Retta Francesca , Piovesan Alessandro , Arvat Emanuela

Background: Immune checkpoint inhibitors (ICIs) showed impressive results in several malignancies; however, a large spectrum of immune-related adverse events (IRAEs) may occur, including thyroid dysfunction (DYSTHYR). IRAEs seem to be associated with better cancer outcome; limited data suggested that thyroid toxicity could be a predictor of response to ICIs.Patients and methods: We retrospectively evaluated all patients who started treatment with the pro...